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The Signal

Expert insights and opinions on clinical research and drug development.

Expert insights and opinions on clinical research and drug development.

A Modular Approach to PROM Implementation – Reflections from ISPOR Europe 2022

Patient-reported outcome measures (PROMs) that measure health-related quality of life (HRQOL) in clinical trials are often composed of several different…

Computerized Adaptive Tests: A Primer

Most patient-reported outcome measures (PROMs) are composed of a fixed number of items – that is, a question and its…

Track and Cumulate Temperature Excursion Data Easily with Signant’s New Supplies Solution

In our post-pandemic world following COVID-19 and its many vaccine development and supplies challenges, a renewed focus has been placed…

Prepare for These 4 Common Scale Management Challenges

Due to Signant’s extensive eCOA and scale management experience, we recognize that these processes can be unexpectedly complex, cumbersome, and…

ISCTM 2022: Scientific Posters Compilation

Signant’s neuroscience team and CNS experts presented scientific posters at the 2022 Autumn Conference hosted by the International Society for…

Application Programming Interfaces (APIs) in Randomization and Trial Supply Management (RTSM)

With an increased number of players involved in conducting clinical research, from Contract Research Organizations (CROs) to sponsors and from…

AAIC 2022: Scientific Posters Compilation

Signant’s neuroscience team and CNS experts presented scientific posters at the 2022 Alzheimer’s Association International Conference in San Diego, California,…

5 Tips for Electronically Migrating and Implementing ClinROs

Filling in the Gap in eClinRO Guidance Nearly 15 years ago, the FDA first published its final guidance on migrating…

Innovation: Using Smartphone Sensors to Instrument At-Home Stair-Climbing Performance Tests

The drive to collect richer insights during drug development, and to optimize protocols by enabling more remote assessment with fewer…

Get to Know the SME – Lew Fredane

Were you always interested in neurology? If not, what did you originally want to be and why?  Not at all –…